ABSTRACT
Exercise electrocardiography (XECG) is a widely used noninvasive test for screening coronary artery disease that is endorsed by current clinical guidelines. However, its clinical use is limited by its modest diagnostic accuracy. Coronary computed tomographic angiography (CCTA) has emerged as a new tool for screening coronary artery disease. In this issue, CCTA performed better diagnostically than XECG when invasive coronary angiography was used as the diagnostic standard. In addition, invasive coronary angiography was chosen based on CCTA, rather than XECG. Although this study suffers from the lack of an appropriate diagnostic standard, the clinical course identified implies that clinical practice might be influenced by sophisticated anatomical imaging to a considerably greater extent than by a simple physiological assessment.